Describe your application, the conditions in which the nanoparticles must operate, and the performance target you are working toward. Formulation and testing scope can then be added once the particle specification is defined with NanoBrand’s team.
Custom Nanoparticle Synthesis and R&D Services
Custom nanoparticle synthesis involves designing and producing gold or silver nanoparticles to meet the requirements of a specific application. Parameters such as particle size, shape, surface chemistry, concentration and optical properties are tailored for each project.
NanoBrand’s scientific team supports development from initial feasibility studies through process optimization, scale-up and the delivery of application-ready material. All nanoparticles are manufactured in Canada and characterized lot by lot for properties such as size distribution, morphology, surface charge and optical response.
Custom synthesis, formulation development and testing
NanoBrand offers three services based on its gold and silver nanoparticle platforms. The scope and capabilities of each service are outlined below.
-
Custom Synthesis
NanoBrand’s scientific team designs and synthesizes gold and silver nanoparticles tailored to specific applications. Particle size, morphology, surface chemistry, concentration and plasmonic properties can be customized to meet defined performance requirements.
Projects may range from early-stage feasibility studies and formulation development to application-ready materials for diagnostics, bioimaging and biosensing, as well as gold nanoparticles for drug delivery research. NanoBrand’s team includes experienced PhD scientists and chemists specializing in life-science nanotechnology and gold and silver nanoparticle development.
-
Nanoparticle Formulation Development
NanoBrand adapts its gold and silver nanoparticles to the requirements of proprietary formulations, delivering optimized nanoparticle formulations ready for testing. The service is designed for CROs and corporate R&D teams seeking a complete nanoparticle-based solution developed by the same manufacturer that produces and characterizes the particles.
Starting materials include nanoparticles in multiple sizes, shapes and surface chemistries. NanoBrand’s formulation specialists work with the client’s team to translate project objectives into an optimized formulation matched to the intended buffer, target analyte, assay format or delivery route.
-
Nanoparticle Testing Services
NanoBrand designs and manages testing studies for gold- and silver-nanoparticle formulations, including:
- Antimicrobial activity and efficacy testing
- Antibody attachment and conjugation efficiency
- Application-specific in vitro testing
- Stability testing under defined storage, buffer and application conditions.
Studies may involve academic and clinical collaborators, generating interpretable data to support formulation development, performance assessment and, where appropriate, regulatory or translational decisions. Particles characterization, including TEM, DLS, Zeta potential, UV–Vis spectroscopy, EDS and ICP-MS, are available as a separate service.
What NanoBrand controls in Custom Synthesis
Each parameter below can be specified for a project, based on capabilities NanoBrand already offers and verifies across its product catalogue. The table summarizes these capabilities; project-specific requirements are defined in collaboration with the client’s team.
| Parameter | What NanoBrand controls |
|---|---|
| Material | Gold (AuNPs) and Silver (AgNPs) |
| Particle Size | Catalogue gold spheres from 5 to 200 nm; custom sizes on request |
| Size Distribution | Coefficient of variation (CoV) at or below 5 % and polydispersity index (PdI) at or below 0.1 on spherical gold of 10 nm and larger, as specified in the catalogue |
| Shape | Spherical particles and branched gold nanostars |
| Surface Chemistry | Citrate, PEG-carboxylate, PVP or chitosan on nanostars, stabilizer-free silver; custom surface chemistry available |
| Optical Reponse | Set through size and shape |
| Characterization Methods | TEM with EDS, DLS, Zeta potential, UV-vis and ICP-MS, through the characterization service |
| Lot Data | Lot-specific characterization on every order; nanoparticles are characterized for core size, size distribution, hydrodinamic diameter, Zeta-potential and plasmon peak position |
| Scale | Development quantities; bulk manufacturing under GMP guidelines once the specification is fixed |
| Lead Time | 2 to 3 weeks on standard orders |
| Manufactured in | Canada, at the NanoBrand facility |
Catalogue values reflect products NanoBrand currently offers. Custom projects are specified and evaluated using the same measurement criteria.
What to provide, what you receive
A custom synthesis project begins with your application requirements, not a catalogue part number. Depending on the agreed scope, NanoBrand delivers nanoparticles alone, a ready-to-test formulation, or nanoparticles accompanied by study data.
| What to provide | What you receive |
|---|---|
| Intended application and performance targets | Proposed project specifications and quotation |
| Buffer conditions and sample matrix | Gold or silver nanoparticles manufactured to the agreed specifications |
| Target analyte or delivery route | Ready-to-test formulation, if formulation development is included |
| Regulatory requirements for the final product | Lot-specific characterization data |
| Existing formulation, if applicable | Antimicrobial, conjugation-efficiency, stability, or in vitro performance data, if testing is included |
Tell us about your Project
